Deborah M Proctor Selected Research

chromium hexavalent ion

8/2021	Inhalation cancer risk assessment for environmental exposure to hexavalent chromium: Comparison of margin-of-exposure and linear extrapolation approaches.
1/2020	An adverse outcome pathway for small intestinal tumors in mice involving chronic cytotoxicity and regenerative hyperplasia: a case study with hexavalent chromium, captan, and folpet.
5/2019	Review of transcriptomic responses to hexavalent chromium exposure in lung cells supports a role of epigenetic mediators in carcinogenesis.
1/2018	Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin-of-exposure values for hexavalent chromium.
12/2017	Comparison of Toxicity and Recovery in the Duodenum of B6C3F1 Mice Following Treatment with Intestinal Carcinogens Captan, Folpet, and Hexavalent Chromium.
11/2017	Ten factors for considering the mode of action of Cr(VI)-induced gastrointestinal tumors in rodents.
1/2017	High-Throughput Screening Data Interpretation in the Context of In Vivo Transcriptomic Responses to Oral Cr(VI) Exposure.
1/2017	Assessment of the mutagenic potential of hexavalent chromium in the duodenum of big blue® rats.
12/2016	Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment.
4/2016	Comparison of in vivo genotoxic and carcinogenic potency to augment mode of action analysis: Case study with hexavalent chromium.

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Deborah M Proctor Research Topics

Disease

32	Neoplasms (Cancer) 08/2021 - 05/2002
10	Hyperplasia 01/2020 - 09/2011
9	Carcinogenesis 05/2019 - 09/2011
5	Lung Neoplasms (Lung Cancer) 05/2019 - 05/2002
3	Intestinal Neoplasms (Intestinal Cancer) 01/2017 - 05/2014
2	Inflammation (Inflammations) 11/2014 - 01/2011
1	Iron Deficiencies 03/2014
1	Anemia 03/2014
1	Carcinoma (Carcinomatosis) 03/2013
1	Adenoma (Adenomas) 03/2013
1	Rectal Neoplasms (Rectal Cancer) 08/2010
1	Esophageal Neoplasms (Esophageal Cancer) 08/2010
1	Digestive System Neoplasms (Cancer of the Digestive System) 05/2002

Drug/Important Bio-Agent (IBA)

29	chromium hexavalent ionIBA 08/2021 - 05/2002
16	Drinking WaterIBA 01/2018 - 05/2002
6	CarcinogensIBA 12/2017 - 05/2002
3	ChromatesIBA 03/2016 - 08/2010
3	sodium bichromate (sodium dichromate)IBA 06/2013 - 01/2012
2	folpet (Phaltan)IBA 01/2020 - 12/2017
2	CaptanIBA 01/2020 - 12/2017
2	MetalsIBA 01/2020 - 08/2016
2	ethyl acrylateIBA 07/2018 - 07/2018
2	Proteins (Proteins, Gene)FDA Link 01/2017 - 11/2014
2	DNA (Deoxyribonucleic Acid)IBA 01/2015 - 01/2011
1	Biological ProductsIBA 05/2019
1	cobalt sulfateIBA 08/2016
1	CobaltIBA 08/2016
1	Codon (Codons)IBA 06/2013
1	GATIBA 06/2013
1	IronIBA 01/2012
1	CytokinesIBA 01/2012